Anti-ASH2L Antibody

This rabbit polyclonal reagent targets ASH2L, a core scaffolding subunit of the MLL/SET1 histone H3K4 methyltransferase complex that regulates transcriptional activation and is implicated in mixed lineage leukemia and hematopoiesis. From Antibodies.com, the unconjugated IgG antibody is supplied as a 100 µl aliquot and is validated for western blot and immunofluorescence workflows against human and mouse samples.

ASH2L (also known as ASH2-like or Bre2 in yeast) interacts directly with WDR5, RBBP5, and MLL to facilitate trimethylation of histone H3 at lysine 4, an epigenetic mark enriched at active promoters. Researchers studying chromatin remodeling, leukemia pathogenesis, and stem cell differentiation rely on antibodies that can reliably detect endogenous ASH2L protein under denaturing and native conditions.

• Host species: Rabbit; Clonality: Polyclonal; Isotype: IgG
• Conjugate: Unconjugated for flexible secondary antibody pairing
• Reactivity confirmed on Human and Mouse specimens
• Applications: western blot (WB) and immunofluorescence (IF)
• Format: liquid vial, 100 µl

Store frozen at -20 °C, with the polyclonal antibody stock divided into small working aliquots to limit freeze-thaw cycles. Provided by Antibodies.com as a research use only reagent for chromatin biology and epigenetics laboratories.