Anti-ASC Antibody

This polyclonal reagent from Antibodies.com targets ASC (Apoptosis-associated Speck-like protein containing a CARD), a key adaptor protein central to inflammasome assembly and pyroptotic signaling in innate immune responses. Raised in rabbit, the antibody recognizes multiple epitopes on the ASC target, supporting detection across blotting and tissue-staining workflows.

Validated for western blot and immunohistochemistry, the unconjugated antibody is supplied as 100 µl of ready-to-use reagent suitable for SDS-PAGE analysis of cell lysates and chromogenic or fluorescent localization in fixed tissue sections. Cross-reactivity has been confirmed against human, mouse, and rat samples, making it a useful reagent for comparative studies in inflammation, apoptosis, and host-defense research.

Researchers commonly deploy this reagent to monitor inflammasome activation, to probe caspase-1 recruitment, or to map ASC expression in disease models involving autoimmune, neurodegenerative, or infectious contexts. Refrigerated storage with protection from light preserves reagent performance across repeated use cycles.