Anti-ART4 Antibody

ART4 (ADP-ribosyltransferase 4), also referred to as the Dombrock blood group carrier protein, is a GPI-anchored mono-ADP-ribosyltransferase expressed on erythrocytes and in several non-hematopoietic tissues. Polyclonal antibodies raised against this target are useful tools for studying Dombrock antigen biology, glycosylphosphatidylinositol-anchored enzyme function, and membrane-associated ADP-ribosylation in both human and murine systems.

This unconjugated rabbit polyclonal reagent from Antibodies.com is validated for Western blot and immunohistochemistry applications, providing flexibility across protein detection workflows. With confirmed reactivity against Human and Mouse samples, the antibody supports translational research where cross-species comparison of ART4 expression is required. The reagent is supplied as 100 µl of polyclonal antiserum suitable for multiple blotting and staining experiments, allowing laboratories to optimize dilutions for their specific protocols.

Researchers investigating erythrocyte surface antigen expression, GPI-anchor biosynthesis, or ART4-mediated transferase activity can use this antibody to probe tissue sections and lysates, supporting studies in transfusion medicine, glycobiology, and cell surface proteomics.