Anti-Arrestin-β-1 Antibody

This Mouse monoclonal antibody targets Arrestin-β-1 (ARRB1), a key scaffolding protein in the β-arrestin signaling pathway that mediates desensitization, internalization, and downstream signaling of G protein-coupled receptors (GPCRs). Produced by Antibodies.com as a purified IgG clone, the reagent is validated for Western Blot (WB) detection in Human, Mouse, and Rat samples, supporting cross-species studies in cardiovascular, neurological, and metabolic research where ARRB1 modulates receptor trafficking and biased agonism.

Supplied at 50 µL per vial in a Tris-Glycine buffer (0.1 M, pH 7.4) containing 150 mM NaCl, 0.2% sodium azide as preservative, and 50% glycerol for stability at -20 °C, the unconjugated format allows flexible pairing with HRP, fluorophore, or biotin secondary reagents. Store aliquots frozen to limit freeze-thaw cycles and protect from light when conjugated downstream. Recommended for signal transduction research, receptor pharmacology, and studies of biased GPCR agonism.