Anti-ARPP-21 Antibody

For researchers profiling cAMP-regulated neuronal phosphoproteins, this unconjugated polyclonal reagent from Antibodies.com binds ARPP-21 across human and mouse samples, with the 100 µl format validated for western blot, immunohistochemistry, and ELISA workflows.

Raised in rabbit, the antibody targets a phosphoprotein most abundant in the basal ganglia and implicated in PP2A regulation and RNA metabolism, supporting studies of dopaminergic signaling, neuronal differentiation, and the link between ARPP-21 dysregulation and neurodegenerative disease or tumor biology, including published associations with tau in Alzheimer's research and with metabolic enzymes in certain cancer contexts.

Because the conjugate is unconjugated, the reagent pairs readily with HRP, biotin, or fluorophore secondaries, allowing chromogenic and fluorescence detection on the same capture reagent.