Anti-ARHGDIG Antibody

This polyclonal antibody from Antibodies.com targets ARHGDIG (Rho GDP Dissociation Inhibitor Gamma), a member of the RhoGDI family that regulates Rho GTPase signaling by sequestering GDP-bound Rho proteins in the cytosol and modulating their membrane cycling. ARHGDIG is preferentially expressed in neural and renal tissues, where it influences cytoskeletal remodeling, neuronal differentiation, and Rnd1/Rnd3-driven signaling pathways that intersect with classical RhoA, Rac1, and Cdc42 cascades.

Supplied as 100 µl of unconjugated rabbit polyclonal antiserum at approximately 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide (pH 7.2), this reagent has been validated for Western blot (WB) and immunocytochemistry (ICC) workflows and shows reactivity with human and mouse samples. Researchers can apply this antibody to studies on Rho GTPase regulation, cytoskeletal dynamics, neuronal RhoGDI signaling, and comparative biology of RHOGDIA, RHOGDIB, and RHOGDIG family members in cell-based and biochemical assays.

Refrigerate the vial upon arrival. For extended storage, aliquot and freeze to limit freeze-thaw cycles, and handle the sodium azide-containing buffer with appropriate laboratory precautions.