Anti-ARHGDIA Antibody

Raised in rabbit against the Rho GDP-dissociation inhibitor alpha (ARHGDIA) protein, this unconjugated polyclonal antibody from Antibodies.com supports detection of the endogenous target across three orthogonal workflows: western blot, immunohistochemistry on fixed sections, and immunofluorescence imaging.

Validated reactivity spans human, mouse, and rat samples, enabling comparative studies in cell lines, primary cultures, and tissue specimens from each species. Each vial contains 100 µl of liquid-format reagent suitable for multiple blotting membranes or staining sessions, with the polyclonal mixture providing coverage of multiple epitopes on the RhoGDIα protein — a cytosolic regulator that sequesters Rho family GTPases and modulates cytoskeletal dynamics, cell migration, and vesicle trafficking.

Common research contexts include investigations of Rho GTPase signaling, epithelial-to-mesenchymal transition in cancer models, neutrophil and lymphocyte chemotaxis assays, neuronal outgrowth studies, and the contribution of RhoGDIα dysregulation to inflammatory and proliferative disease pathways. The unconjugated format gives researchers full flexibility to pair the antibody with HRP, fluorophore, or biotin secondary reagents chosen for their preferred detection platform.