Anti-ARHGAP30 Antibody

Polyclonal reagent targeting ARHGAP30, a Rho GTPase-activating protein implicated in cytoskeletal regulation, cell migration, and reported contributions to tumor invasion pathways in several carcinoma models. Supplied by Antibodies.com as an unconjugated rabbit polyclonal antibody at 1 mg/ml in phosphate buffered saline (PBS) containing 15 mM sodium azide at approximately pH 7.2, the product ships in a 100 µl vial.

Validated for western blot detection of endogenous ARHGAP30 in human, mouse, and rat samples, the antibody supports comparative studies across cell lines and tissue lysates. Published work has linked ARHGAP30 to colorectal and hepatocellular carcinoma behavior, where altered Rho GTPase signaling modulates proliferation and motility readouts in vitro. Researchers employ this reagent to track expression shifts following gene knockdown, pathway inhibition, or experimental stimulation.

The vial should be refrigerated upon arrival to preserve activity and protected from light; aliquoting after first thaw reduces freeze-thaw stress on the immunoglobulin fraction. Sodium azide serves as a microbial preservative, so the reagent is restricted to research use only and is not intended for diagnostic or therapeutic applications.