Anti-AR (phospho S650) Antibody - Identical to Abcam (ab194866)

This rabbit polyclonal antibody from Antibodies.com targets the androgen receptor (AR) phosphorylated at serine 650, a post-translational modification linked to AR nuclear translocation and transcriptional activation in hormone-responsive tissues. Raised in rabbits and affinity-purified as an IgG preparation, the reagent is supplied unconjugated at 100 µl per vial, giving laboratories flexibility to pair it with their own secondary detection systems and chromogens.

Validated for immunohistochemistry (IHC), the antibody enables visualization of phospho-S650 AR in formalin-fixed paraffin-embedded tissue sections, supporting studies of prostate cancer biology, androgen-driven signalling, and steroid receptor pharmacology. Reactivity has been confirmed against human samples, with the phospho-specific epitope allowing researchers to distinguish activated receptor pools from total AR in tumour and normal tissue contexts.

The unconjugated format suits standard IHC workflows using HRP- or alkaline phosphatase-based secondary reagents. Storage temperature: keep refrigerated; protect from light and avoid repeated freeze-thaw cycles to preserve phospho-epitope recognition. Each lot is quality controlled to deliver reproducible staining intensity across runs.