Anti-AR-β2 (R228) Antibody

This rabbit polyclonal reagent from Antibodies.com targets the β2-adrenergic receptor (ADRB2), with reactivity confirmed against Human, Mouse, and Rat samples. The immunogen corresponds to a region that includes residue R228 within the third intracellular loop, an area involved in coupling to Gs proteins and downstream cAMP signaling. Researchers apply this reagent to Western blot and immunohistochemistry workflows to examine receptor expression, tissue distribution, and signaling in studies related to airway pharmacology, cardiac physiology, and metabolic regulation.

Each vial provides 100 µl of unconjugated antibody at 1 mg/ml in phosphate buffered saline (PBS), approximately pH 7.2, with 0.05% sodium azide added as preservative. The polyclonal format enables recognition of multiple epitopes on the target for reliable detection across blots and stained sections. For handling, store refrigerated at 4°C for short-term use, or freeze at -20°C in working aliquots to preserve activity across multiple freeze-thaw cycles. Protect from light and avoid repeated temperature shifts when thawing for experiments.