Anti-Aquaporin 4 Antibody

Aquaporin 4 (AQP4) is the predominant water channel protein in the central nervous system, densely localized on astrocyte endfeet that interface with cerebral vasculature. This unconjugated Mouse monoclonal antibody from Antibodies.com binds AQP4 and supports clear detection of the channel in Western blot and immunofluorescence workflows. The reagent is supplied as 100 µl of liquid and reacts with Human, Rat, and Mouse samples, making it useful across comparative neuroscience and renal physiology studies that probe AQP4 distribution in brain, spinal cord, optic nerve, and kidney collecting duct tissue. Because AQP4 is the established autoantigen in neuromyelitis optica spectrum disorder, this antibody is widely cited in NMO-related research aiming to characterize astrocyte pathology, orthogonal array assembly, and blood-brain barrier function. Researchers investigating brain edema, traumatic injury models, or aquaporinopathies will find the unconjugated format flexible for direct conjugation or for pairing with custom secondary reagents.