Anti-APTX Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent is raised against aprataxin (APTX) and validated for use in Western blot (WB) and immunohistochemistry (IHC) workflows. It detects the endogenous total APTX protein in human, mouse, and rat samples, with the immunogen being a recombinant human APTX protein and the antibody subsequently affinity-purified against that immunogen. The unconjugated antibody is supplied at 1.0 mg/mL in a 50 µL aliquot, prepared in phosphate-buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a stabiliser. Because the reagent is provided unconjugated, it can be flexibly labelled or used directly in standard immunodetection protocols. Polyclonal antibodies typically recognise multiple epitopes on the target, which can be advantageous when working with samples where a single monoclonal epitope may be masked or lost. Researchers studying DNA repair pathways, including the resolution of abortive DNA ligation intermediates linked to Ataxia with Oculomotor Apraxia type 1, will find this reagent useful for characterising APTX expression across a range of tissues and cell types. The product belongs to the Antibodies.com primary antibodies catalogue and ships with the documentation needed for routine laboratory use, including recommended starting dilutions for the validated WB and IHC applications.