Anti-APRT Antibody

Adenine phosphoribosyltransferase (APRT) is a key enzyme in the purine salvage pathway, catalyzing the magnesium-dependent synthesis of AMP from adenine and 5-phosphoribosyl-1-pyrophosphate. This unconjugated rabbit polyclonal reagent from Antibodies.com targets the human APRT protein and is supplied as 100 µl of polyclonal antiserum suited to western blot, immunohistochemistry, and immunofluorescence workflows. The antibody recognizes the native human enzyme and is offered in a research-use-only format for studies of nucleotide metabolism, 2,8-dihydroxyadenine urolithiasis linked to APRT deficiency, and tumor cell biology where purine salvage contributes to proliferation. Polyclonal reactivity across multiple APRT epitopes supports detection in tissue sections and cell-based imaging, and the unconjugated format allows researchers to pair the reagent with secondary antibodies and detection chemistries of their choice.