Anti-APRIL Antibody

Raised in rabbit against the TNFSF13 cytokine, this unconjugated polyclonal antibody recognizes APRIL (A Proliferation-Inducing Ligand), a TNF-family ligand that signals through TACI and BCMA receptors on B-lineage cells. The reagent from Antibodies.com is supplied as a 100 µl liquid aliquot and is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows on human, mouse, and rat samples. Researchers studying germinal center formation, immunoglobulin class-switch biology, or autoantibody-driven disease models use APRIL detection to track ligand expression in lymphoid tissue and to distinguish APRIL-positive cells from related TNF-family members such as BAFF. Because the antibody is unconjugated, it can be paired with HRP, biotin, or fluorophore-labeled secondaries of the investigator's choice, and the polyclonal format increases the likelihood of recognizing multiple epitopes on both the membrane-bound and soluble forms of the ligand. Aliquot upon receipt; for short-term storage keep refrigerated, and for longer periods freeze at -20 °C in working aliquots to limit freeze-thaw cycles.