Anti-APP delta C31 Antibody

The Anti-APP delta C31 antibody from Antibodies.com is a rabbit polyclonal reagent raised against the C-terminal 31 amino acid caspase-generated fragment of the Amyloid Precursor Protein (APP). This unconjugated IgG preparation is supplied as a liquid in a 100 µl vial and has been validated for use in western blot (WB), immunocytochemistry (ICC), and ELISA applications.

The antibody cross-reacts with samples from human, mouse, and rat species, supporting translational studies of APP processing and caspase-mediated cleavage events. It recognises the APP delta C31 fragment produced by caspase cleavage at the Asp664 site, making it a relevant tool for research into amyloidogenic pathways, apoptotic signalling, and Alzheimer disease-associated neurotoxicity.

Storage and handling: store aliquots at -20 °C and avoid repeated freeze-thaw cycles to preserve antibody activity. Recommended working dilutions vary by application; for western blotting, typical use ranges from 1:500 to 1:2000 depending on sample preparation. For research use only.