Anti-APP (Ab-668) Antibody

Phosphorylation of amyloid precursor protein (APP) at threonine 668 is a post-translational modification of central interest in studies of neuronal signaling and Alzheimer's disease pathology. This polyclonal reagent from Antibodies.com was raised in rabbit against the Ab-668 epitope and is supplied as an unconjugated preparation at 100 µl, validated for Western blot and immunofluorescence workflows on samples derived from human, mouse, and rat tissues. Researchers use this antibody when examining APP processing, the distribution of phospho-Thr668 species in neural cell lines, and how kinase activity influences APP cleavage products such as Aβ. The unconjugated format allows flexible pairing with secondary antibodies labeled with HRP, fluorophores, or biotin depending on the chosen detection platform. Each vial supports both fixed-cell imaging and standard immunoblotting protocols in research use only settings.