Anti-Apoptosis-enhancing nuclease Antibody

Raised in rabbit against the human apoptosis-enhancing nuclease (AEN) target, this unconjugated polyclonal reagent from Antibodies.com is supplied as a 100 µl liquid aliquot. AEN, also known as ISG20L1, is a 3'-to-5' exonuclease implicated in p53-dependent DNA fragmentation during programmed cell death, which makes this antibody a useful probe for studying apoptotic pathways and DNA damage responses in cultured cells and tissue sections. The antibody is validated for western blot and immunohistochemistry on human samples and binds the target in its native context, supporting both chromogenic and fluorescence detection workflows. Store at -20°C in working aliquots to limit freeze-thaw cycles and preserve reagent activity for repeat use.