Anti-APOBEC3C Antibody

Produced in rabbit hosts and supplied by Antibodies.com, this unconjugated IgG polyclonal primary antibody recognizes the cytidine deaminase APOBEC3C, a member of the APOBEC3 family located on chromosome 22 that has been studied for its contributions to retroviral restriction and to cancer mutational signatures. The reagent is delivered as 200 µl of stock solution and is validated for immunofluorescence (IF) applications on human samples, supporting investigators who need to map subcellular distribution of APOBEC3C in fixed cells and tissue sections.

Because the antibody is unconjugated, it can be paired with any fluorophore-conjugated secondary reagent, allowing flexible panel design in single-plex or multi-target immunofluorescence experiments. The polyclonal clonality provides binding across multiple epitopes of the target, which is useful when probing full-length APOBEC3C in overexpression systems or when a single monoclonal epitope may be masked. The IgG isotype is compatible with standard anti-rabbit secondary detection reagents commonly used in fluorescence imaging workflows.

Researchers studying APOBEC3C biology have used antibodies of this kind to investigate cytoplasmic expression patterns, since the enzyme engages single-stranded DNA substrates during cytidine deamination events. The reagent should be refrigerated and handled under standard antibody storage conditions to preserve binding activity over multiple freeze-thaw cycles. For research use only.