Anti-APOA1 Antibody

This rabbit polyclonal antibody from Antibodies.com specifically recognizes Apolipoprotein A-I (APOA1), the principal protein constituent of high-density lipoprotein (HDL) particles. APOA1 mediates reverse cholesterol transport by promoting cholesterol efflux from peripheral tissues and serves as a cofactor for lecithin-cholesterol acyltransferase (LCAT), making it a key target in cardiovascular and metabolic disease research.

Supplied as 100 µl of unconjugated reagent at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC) applications. The polyclonal preparation shows reactivity with Human, Mouse, and Rat samples, supporting cross-species studies of lipid metabolism, atherosclerosis, and HDL biology.

Store refrigerated to preserve antibody activity and protect from light; aliquot to limit freeze-thaw cycles. Researchers studying apolipoprotein disorders, Tangier disease, familial HDL deficiency, and cardiovascular biomarkers can use this reagent to detect endogenous APOA1 expression in tissue sections and cell lysates. The product is delivered in a single vial format for research use only.