Anti-APLF (Ab-116) Antibody

Raised in rabbit against APLF, this unconjugated polyclonal reagent from Antibodies.com targets a region centered on residue 116 of the human protein and is supplied as 100 µl of ready-to-use antibody.

APLF (aprataxin and PNK-like factor) participates in the cellular DNA damage response, acting at chromatin to promote non-homologous end joining and to recruit XRCC4/DNA Ligase IV to broken ends, so the antibody is used to probe APLF expression and post-translational modification in human samples.

Validated applications include Western blot and immunohistochemistry, with reactivity confirmed against human tissue and cell line lysates; secondary detection is carried out with standard anti-rabbit IgG reagents. The polyclonal format broadens epitope coverage, which is useful for tracking endogenous APLF across multiple lysate or fixation conditions. Shipped refrigerated for stability, the antibody is intended for research use only and pairs well with chromatin fractionation protocols that interrogate DNA repair signaling.