Anti-APIP Antibody

This polyclonal antibody from Antibodies.com targets APIP (APAF1-Interacting Protein), a mitochondrial enzyme that participates in the methionine salvage pathway and modulates APAF-1-dependent apoptotic signaling. Raised in rabbit and purified as an unconjugated IgG preparation, the reagent is supplied at 1 mg/ml in PBS supplemented with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. It is validated for Western blot and immunohistochemistry workflows and shows reactivity with human, mouse, and rat samples. APIP, also known as MIP, is of interest in cancer biology research because its expression has been linked to cell survival under stress conditions, and the protein has been examined as a prognostic indicator in lung and gastric tumor studies. The glycerol-containing buffer supports convenient storage at -20 °C without freeze-thaw damage and is compatible with standard immunoblotting protocols run on whole-cell or tissue lysates. The sodium azide acts as a preservative to protect the IgG fraction during routine handling. As a research use only reagent, this polyclonal antibody is intended for laboratory studies of apoptosis regulation and methionine metabolism, and it is not cleared for diagnostic procedures.