Anti-APBB2 Antibody

This polyclonal antibody reagent from Antibodies.com targets APBB2, a member of the FE65 family of adapter proteins that interact with the amyloid precursor protein (APP) intracellular domain. The rabbit-derived polyclonal reagent is unconjugated and supplied as 100 µl in a liquid format optimized for western blot (WB) and immunohistochemistry (IHC) workflows. It has been validated for reactivity with human and mouse samples, supporting cross-species experimental designs in neurobiology and cell signaling research. Typical applications include probing APBB2 expression in brain tissue sections, transfected cell lines, and relevant model systems, as well as studying protein-protein interactions within the APP signaling complex. The polyclonal format recognizes multiple epitopes across the target, which can improve detection of alternatively spliced isoforms or post-translationally modified protein variants compared with monoclonal reagents. Storage and handling recommendations from Antibodies.com generally include aliquoting upon receipt to minimize repeated freeze-thaw cycles, and storing at -20 °C to preserve antibody binding activity over extended periods. Intended for research use only in laboratory settings and not for diagnostic or therapeutic applications.