Anti-APAF-1-ALT Antibody

Apoptosis research applications benefit from isoform-specific detection of APAF-1-ALT, a shorter splice variant of the canonical apoptosome scaffold protein implicated in mitochondrial cell death pathways. Antibodies.com supplies this unconjugated rabbit polyclonal reagent validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples, sold for research use only. Each vial contains 100 µl of polyclonal antiserum in a ready-to-use liquid format; store refrigerated at 4 °C for short-term handling or aliquot and freeze at -20 °C for long-term storage, avoiding repeated freeze-thaw cycles to preserve binding activity. The antibody supports visualization of the alternative APAF-1 transcript in fixed tissue sections and cultured cell lines, useful in tumor biology studies, neurodegeneration research, and investigations of intrinsic apoptotic signaling where distinguishing the ALT isoform from full-length APAF-1 matters.