Anti-AP2A1 Antibody

AP2A1 encodes the alpha-adaptin subunit of the adaptor protein complex 2 (AP-2), a heterotetrameric coat component essential for clathrin-mediated endocytosis at the plasma membrane. This polyclonal reagent from Antibodies.com is raised in rabbit and supplied unconjugated at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, with a 100 µl vial size suitable for multiple experiments.

It has been validated across Western blot, immunoprecipitation, and immunohistochemistry workflows, and recognizes the AP2A1 target in human, mouse, and rat samples. Researchers commonly deploy it to study cargo recognition during vesicle formation, receptor trafficking, and the membrane-coat dynamics that underlie synaptic vesicle recycling and nutrient uptake.

The glycerol-supplemented buffer keeps the antibody stable for routine bench handling, while sodium azide preserves it against microbial contamination during repeated use. As an unconjugated primary antibody, it remains compatible with secondary antibody systems chosen by the end user — HRP, fluorophore, or biotin conjugates — supporting flexibility across immunoblotting, immunoprecipitation, and tissue-staining protocols.