Anti-AOC3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets AOC3 (amine oxidase copper-containing 3), a copper-dependent semicarbazide-sensitive amine oxidase that is displayed on vascular endothelium as the adhesion protein VAP-1. The reagent is supplied as 100 µl of a 1 mg/ml stock in PBS, preserved with 0.1% sodium azide and stabilized with 50% glycerol, and is unconjugated so it can be paired with a secondary reporter of the researcher's choice.

Validated applications include Western blot, immunohistochemistry on formalin-fixed sections, and immunofluorescence on cultured cells and cryosections. Reactivity has been confirmed against human, mouse, and rat AOC3, supporting cross-species studies of leukocyte rolling, vascular inflammation, hepatic injury, atherosclerosis, and amine-metabolism changes in diabetes research models.

Raised in rabbit, the polyclonal reagent recognizes multiple epitopes on the AOC3/VAP-1 glycoprotein, which is useful for detecting splice variants and post-translationally modified forms. Each vial is intended for research use only; refrigerated storage is recommended and small aliquots help limit freeze-thaw cycles of the glycerol-containing stock.