Anti-ANXA8 Antibody

Generated in rabbit as a polyclonal reagent, this unconjugated primary antibody recognizes human Annexin A8 (ANXA8), a calcium-dependent phospholipid-binding protein of the annexin family encoded on chromosome 10q11.22. The antibody is supplied as 100 µl of liquid and is validated for Western Blot (WB) and Immunohistochemistry (IHC) workflows on human samples, making it a practical choice for labs investigating annexin biology in tumor and cell biology contexts.

ANXA8 has attracted research interest in several disease areas. It is overexpressed in subsets of triple-negative breast cancer and in hepatocellular carcinoma, where it has been linked to proliferation, migration, and invasion phenotypes, and the gene has been studied in relation to fibrinolysis and placental biology as well. Researchers using this Antibodies.com reagent can probe endogenous ANXA8 levels across cell lines and tissue sections to extend those observations in their own systems.

Because the antibody is unconjugated, it pairs cleanly with any HRP, fluorescent, or biotin-based secondary detection system a lab already has on hand, and the polyclonal format offers broader epitope coverage than a monoclonal reagent would. Recommended storage at -20 °C in working aliquots helps preserve activity across multiple freeze-thaw cycles.