Anti-ANTXR2 Antibody

Polyclonal rabbit antibody raised against ANTXR2 (anthrax toxin receptor 2), a cell-surface protein also known as CMG2. ANTXR2 serves as a receptor for anthrax protective antigen and participates in capillary morphogenesis, basement-membrane interaction, and endothelial cell adhesion. The reagent from Antibodies.com is supplied as an unconjugated antiserum at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial.

Validated for Western blot (WB) and immunohistochemistry (IHC) on human samples, this polyclonal reagent targets an extracellular region of the ANTXR2 transmembrane protein. Investigators working on juvenile hyaline fibromatosis, infantile systemic hyalinosis, tumour angiogenesis, or anthrax pathogenesis use it on cultured cells and on formalin-fixed paraffin-embedded (FFPE) tissue sections. The polyclonal format broadens epitope recognition, which is useful when single-residue variation is a concern.

Store the vial at -20°C, protect from light, and aliquot on first use to limit freeze-thaw cycles. Dilute in blocking buffer for immunostaining or in 5% non-fat milk in TBS-T for membrane probing, following individual laboratory optimisation.