Anti-ANT3 Antibody

The rabbit polyclonal antibody from Antibodies.com targets ANT3 (Adenine Nucleotide Translocator 3, also known as SLC25A6), a mitochondrial inner membrane carrier protein that exchanges matrix ATP for cytosolic ADP across the inner mitochondrial membrane, a step central to oxidative phosphorylation and cellular energy homeostasis.

Supplied as 100 µl of unconjugated antiserum raised in rabbit, the reagent is validated for Western blot, immunohistochemistry, and ELISA workflows on human samples. ANT3 is one of three adenine nucleotide translocase isoforms encoded in the human genome; the gene is located on the X chromosome and is expressed across oxidative tissues such as heart and skeletal muscle, with roles reported in mitochondrial bioenergetics, apoptosis regulation, and carrier protein family biology.

The unconjugated format provides flexibility to pair the primary antibody with HRP-conjugated, fluorescently labelled, or biotinylated secondary reagents depending on the detection platform. Researchers commonly apply this reagent in cell culture lysates and fixed tissue sections to characterise mitochondrial transporter expression. For handling, refrigerate short term and aliquot the antiserum to limit repeated freeze-thaw cycles that can compromise polyclonal activity.