Anti-ANLN Antibody

Anillin (ANLN) is an actin-binding protein that localizes to the cleavage furrow during cytokinesis, where it coordinates contractile ring dynamics and membrane ingression. This unconjugated rabbit polyclonal antibody from Antibodies.com targets ANLN for detection by Western blot and immunofluorescence in human samples. Supplied as a 100 µL aliquot, the reagent supports investigations into mitotic progression, cytoskeletal remodeling, and aberrant cell division linked to tumor proliferation.

Researchers studying anillin overexpression in carcinomas, RhoA signaling during abscission, or actin-myosin contractility can pair this primary antibody with standard chemiluminescent or fluorescent secondary reagents to resolve the endogenous ~124 kDa anillin band on immunoblots and visualize furrow-associated localization in fixed cells. The polyclonal format broadens epitope coverage for detecting anillin across its functional domains, useful when probing phosphorylation-dependent regulation during late-stage mitosis.