Anti-ANGPTL4 Antibody

Raised in rabbit against the angiopoietin-like 4 (ANGPTL4) target, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µL of a 1 mg/mL stock in PBS with 0.1% sodium azide and 50% glycerol as a cryostabilizer. ANGPTL4 is a secreted glycoprotein best known for acting as a hormonal brake on lipoprotein lipase, positioning it as a focal readout in studies of triglyceride clearance, fatty acid oxidation, and the metabolic crosstalk between adipose, liver, and muscle tissue under fasting, hypoxia, and refeeding.

Validated for Western blot, immunohistochemistry, and immunofluorescence, the antibody recognizes the endogenous antigen across human, mouse, and rat samples, supporting comparative work in metabolic disease models, tumor hypoxia and angiogenesis studies, and inflammation-linked tissue remodeling. Investigators probing ER stress, PPAR pathway activity, and the tumor microenvironment use ANGPTL4 as a marker of nutrient stress and vascular remodeling, and the unconjugated format gives researchers freedom to pair it with their preferred secondary or affinity capture system rather than being locked to a specific label.

Storage at -20 °C in single-use aliquots minimizes freeze-thaw damage to the polyclonal pool, and brief equilibration to room temperature before opening limits condensation around the vial. Sodium azide is included at 0.1% to suppress microbial growth, while the 50% glycerol component keeps the antibody liquid and usable directly from cold storage for routine blotting without an intermediate dilution step.