Anti-ANGPTL3 Antibody

ANGPTL3 (Angiopoietin-like protein 3) is a liver-secreted regulator of lipid metabolism that suppresses lipoprotein lipase and endothelial lipase activity, governing circulating triglyceride and HDL-cholesterol levels. Loss-of-function studies in humans and rodent models have linked reduced ANGPTL3 activity to lower plasma lipids, making it a focus of cardiovascular and metabolic disease research, including work on dyslipidemia, atherosclerosis, and lipid-lowering therapeutic strategies.

This unconjugated rabbit polyclonal antibody from Antibodies.com is supplied at 1 mg/ml in phosphate buffered saline with 15 mM sodium azide at approximately pH 7.2, supporting Western blot workflows on human, mouse, and rat samples. The reagent is provided as a 100 µl volume suited to investigations of ANGPTL3 expression in hepatic tissue and to lipid-metabolism signaling studies, applied to detection of the target band in whole-cell or tissue lysates.

Intended for research use only, the polyclonal format allows recognition of multiple epitopes on the target, which is useful when probing native or denatured protein in cell and tissue preparations.