Anti-Angptl3 Antibody

Angptl3 (Angiopoietin-like protein 3) is a secreted glycoprotein predominantly expressed in the liver that plays a central role in lipid metabolism by inhibiting lipoprotein lipase and endothelial lipase, regulating plasma triglyceride and HDL cholesterol levels. This unconjugated polyclonal reagent from Antibodies.com is raised in rabbit and validated for Western blot detection of Angptl3 in human, mouse, and rat samples.

Supplied as 100 µl of liquid at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody remains stable when stored at -20 °C and aliquoted to limit freeze-thaw cycles. Researchers working on dyslipidemia, cardiovascular disease mechanisms, and hepatic endocrine signaling rely on this reagent to profile Angptl3 expression across in vivo and in vitro systems. The polyclonal format increases the chance of recognizing multiple epitopes on the target, which is useful when working with denatured lysates prepared for SDS-PAGE and Western blot transfer to nitrocellulose or PVDF membranes.