Anti-Angiotensin Antibody

Raised in rabbit as a polyclonal reagent targeting angiotensin, this unconjugated primary antibody from Antibodies.com supports investigations into the renin-angiotensin system (RAS) and its role in blood pressure regulation, vascular remodeling, and electrolyte homeostasis. The antibody is supplied in a 100 µl vial and is validated for Western Blot and Immunohistochemistry workflows on human-derived samples.

The polyclonal format increases the likelihood of recognizing multiple epitopes across angiotensin peptide variants, which is useful when probing tissue sections for differential expression of angiotensin I, angiotensin II, and related cleavage fragments in cardiovascular, renal, and adrenal research. Because the reagent is unconjugated, it can be paired with a user-selected secondary antibody for chromogenic or fluorescent detection, or used directly in custom labeling schemes such as biotinylation or HRP conjugation.

For immunohistochemistry, antigen retrieval conditions should be optimized empirically for each specimen; paraffin-embedded sections of kidney cortex, adrenal gland, vascular smooth muscle, and cardiac tissue are common reference samples in hypertension studies. For Western Blot, expected band patterns depend on the angiotensin precursor forms present, including angiotensinogen, angiotensin I, and the biologically active angiotensin II octapeptide. Short-term refrigerated storage preserves reagent activity, and aliquoting on arrival helps limit repeated freeze-thaw cycles. Intended for research use only.