Anti-ANG Antibody

This polyclonal antibody from Antibodies.com specifically targets angiogenin (ANG), a 14 kDa secreted ribonuclease in the pancreatic RNase A superfamily that promotes new blood vessel formation and supports stress-induced rRNA transcription in the nucleus. Validated applications cover Western blot (WB) and immunohistochemistry (IHC), with reactivity confirmed against human and mouse angiogenin, supporting comparative studies of angiogenesis, tumor microenvironment biology, and amyotrophic lateral sclerosis where ANG coding mutations have been implicated in disease susceptibility.

The reagent is supplied as 100 µl of unconjugated rabbit polyclonal antiserum at 1 mg/ml in phosphate buffered saline (PBS) with 15 mM sodium azide at approximately pH 7.2. Researchers commonly employ this antibody to probe angiogenin expression in tissue sections and cell lysates, including work on prostate, breast, and colorectal tumor models where angiogenin is upregulated. Refrigerated handling and aliquoting help preserve binding activity across repeated freeze-thaw cycles for extended multi-month campaigns.