Anti-ANAPC4 Antibody

This polyclonal primary antibody from Antibodies.com targets ANAPC4, a core scaffold subunit of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase that drives cell cycle progression through ubiquitin-mediated degradation of securin and cyclin B. Raised in rabbit, the IgG isotype reagent is supplied unconjugated in a 200 µl volume, optimized for Western blot detection of the human protein. Researchers investigating mitotic regulation, checkpoint control, and chromosome segregation can use this reagent to probe APC/C subunit composition across cell lysate preparations, with reactivity confirmed against human samples. For research use only, the unconjugated format supports standard immunoblotting workflows examining APC/C integrity and anaphase onset in dividing cells.