Anti-ANAPC4 Antibody

Raised in rabbits and affinity-purified to target ANAPC4, a core scaffolding subunit of the anaphase-promoting complex/cyclosome (APC/C) that governs ubiquitin-dependent turnover of mitotic regulators such as cyclin B1 and securin. This unconjugated polyclonal IgG reagent from Antibodies.com is validated for Western blot detection of the human protein at its expected molecular weight near 84 kDa. Supplied as 100 µl of working reagent, it supports cell cycle research, mitosis studies, and investigations into APC/C function in transformed and primary cell lines. The antibody binds the endogenous human target in whole-cell lysates, making it a practical tool for probing APC/C integrity, mitotic checkpoint regulation, and chromosome segregation pathways.