Anti-ANAPC2 Antibody

Raised in rabbit against anaphase-promoting complex subunit 2 (ANAPC2), this unconjugated primary antibody from Antibodies.com targets a core scaffold of the APC/C ubiquitin ligase that drives the metaphase-to-anaphase transition, mitotic exit, and ubiquitin-dependent turnover of cyclins and securin. Supplied as 100 µl of polyclonal antiserum, the reagent is validated for western blot (WB) and immunohistochemistry (IHC) and reacts with Human and Mouse samples, making it useful for cell cycle studies, chromosome segregation analyses, and investigations of APC/C dysregulation in tumor models. The unconjugated format leaves reporter choice to the user, allowing coupling to a preferred HRP polymer, biotin, or fluorescent label for chromogenic or immunofluorescence detection on cultured cells and formalin-fixed paraffin-embedded tissue sections. Aliquot upon arrival and store at -20 °C to preserve binding activity across repeated freeze-thaw cycles.