Anti-Anamorsin Antibody

Produced in rabbit as an unconjugated polyclonal IgG preparation, this 100 µl reagent from Antibodies.com recognizes the CIAPIN1 (cytokine-induced apoptosis inhibitor 1) protein, an evolutionarily conserved cytosolic factor essential for iron-sulfur cluster assembly and mitochondrial respiratory complex maturation. The antibody is validated for western blot, immunohistochemistry, and immunofluorescence detection of the human target, enabling studies on apoptosis regulation, oxidative stress responses, and proliferative signaling in tumor cell models.

CIAPIN1 was originally characterized as a downstream effector of cytokine signaling that protects cells from growth factor withdrawal-induced death and has since been linked to chemoresistance in hepatocellular carcinoma, gastric cancer, and acute myeloid leukemia research. The unconjugated format offers flexibility to pair the primary reagent with HRP-, alkaline phosphatase-, fluorophore-, or biotin-conjugated secondary antibodies depending on the detection platform, and the polyclonal response expands epitope coverage for both denatured and mildly fixed samples. For best results, aliquot the antibody upon arrival and store refrigerated, avoiding repeated freeze-thaw cycles to preserve activity across multiple blotting and imaging experiments.