Anti-Amylin Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets amylin, the 37-residue peptide hormone also known as islet amyloid polypeptide (IAPP) that is co-secreted with insulin from pancreatic beta cells. Validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows against human samples, the antibody supports studies of beta-cell biology and the amyloidogenic pathways linked to type 2 diabetes. The polyclonal format broadens epitope coverage, which is useful when probing aggregated or conformationally variable IAPP deposits in fixed tissue sections. Supplied as 100 µl, the unconjugated format pairs readily with user-selected reporter-conjugated secondaries (HRP, biotin, or fluorophore) for flexible detection chemistry. Each laboratory should empirically determine the optimal working dilution using appropriate positive and negative controls. Refrigerate on receipt, avoid repeated freeze-thaw cycles, and aliquot upon first thaw to preserve antibody activity. Research use only.