Anti-AMPKβ1 (1A7) Antibody

This Mouse monoclonal IgG reagent targets the catalytic alpha-1 subunit of AMP-activated protein kinase, a serine/threonine kinase that acts as a cellular energy sensor responding to rising AMP/ATP ratios. The unconjugated antibody, supplied by Antibodies.com as 100 µl of purified protein in 0.1 M Tris-Glycine buffer (pH 7.4) containing 150 mM NaCl, 0.2% sodium azide, and 50% glycerol, is generated from clone 1A7 and validated across multiple experimental platforms including western blot, immunocytochemistry, immunohistochemistry, and immunoprecipitation workflows. Reactivity has been confirmed in human, mouse, rat, and monkey samples, making the reagent versatile for cross-species signaling studies of metabolic regulation, autophagy, and mitochondrial biogenesis. Investigators working on metabolic disease, exercise physiology, or tumor metabolism commonly use anti-AMPKα1 clones to probe phosphorylation at Thr172 and downstream effects on ACC, ULK1, and mTOR pathways. The vial format supports aliquoting for single-use applications and long-term storage at -20°C without significant loss of binding activity.