Anti-AMPH Antibody

This rabbit polyclonal reagent from Antibodies.com targets amphiphysin (AMPH), a neuronal BAR-domain protein that participates in clathrin-mediated synaptic vesicle endocytosis at presynaptic terminals.

The unconjugated antibody is supplied as 100 µl of ready-to-use reagent and has been validated for Western blot and immunohistochemistry workflows on human tissue samples. Because amphiphysin concentrates at nerve terminals, the reagent is commonly used to characterize synaptic architecture, study endocytic coat recruitment, and screen for autoantibody reactivity linked to paraneoplastic stiff-person spectrum disorders.

The polyclonal format provides broad epitope coverage of the human amphiphysin I protein, supporting detection in fixed brain sections as well as in denatured lysates. Researchers investigating neurodegeneration, synaptic transmission, or autoimmune neurology can pair the reagent with secondary antibodies of their choice, since the primary is supplied unconjugated.