Anti-ALPP / ALPPL2 Antibody

This rabbit polyclonal reagent from Antibodies.com targets ALPP and ALPPL2, two closely related members of the human alkaline phosphatase family that share substantial sequence homology in their catalytic core. ALPP encodes the placental alkaline phosphatase isozyme, while ALPPL2 encodes a placental-like variant widely studied as a cancer-testis antigen expressed in germ cell tumors and certain carcinomas. Researchers use this unconjugated primary antibody in western blot workflows to resolve the glycosylated membrane-bound forms of these phosphatases from cell lysates and tissue extracts, and in ELISA-based quantitative assays to compare expression across sample panels. Cross-reactivity has been validated against human and mouse samples, supporting comparative studies in tumor cell lines, patient-derived xenografts, and rodent disease models. Each vial is supplied as 100 µl of liquid formulation, suitable for standard immunoblotting dilutions and plate-coating protocols.