Anti-alpha Tubulin 4a Antibody

Raised in rabbit, this unconjugated polyclonal antibody from Antibodies.com targets the alpha-tubulin 4a (TUBA4A) protein, a major constituent of the microtubule cytoskeleton expressed across human tissues.

TUBA4A has emerged as a gene of interest in motor neuron disease, with missense mutations reported in familial amyotrophic lateral sclerosis (ALS) and overlapping frontotemporal dementia cases, so the reagent supports research into neuronal cytoskeletal organization and tubulin isotype regulation.

The antibody is validated for Western blot, immunohistochemistry, and immunofluorescence on human samples, enabling detection of TUBA4A in cell lysates, fixed tissue sections, and cultured cells.

Supplied as 100 µl of polyclonal antiserum, it is recommended to store at -20°C in working aliquots to limit freeze-thaw cycles and preserve binding activity.

Researchers studying ALS pathology, axon stability, or microtubule-based transport can use this reagent alongside pan-tubulin antibodies to resolve isotype-specific contributions in their preparations.