Anti-ALOX15B Antibody

Raised in rabbit against ALOX15B (arachidonate 15-lipoxygenase type B), a non-heme iron dioxygenase that peroxidizes polyunsaturated fatty acids such as arachidonic and linoleic acid to bioactive lipid hydroperoxides. Antibodies.com supplies the polyclonal reagent at 1 mg/ml in a 100 µl volume, formulated in PBS with 0.1% sodium azide and 50% glycerol as cryoprotectant. Recommended storage is at -20 °C, with single-use aliquots advised to limit freeze-thaw cycles.

Validated for western blot, immunohistochemistry, and immunofluorescence detection of human and mouse ALOX15B in cell lysates, tissue sections, and fixed cellular preparations. The unconjugated format supports flexible secondary reporter conjugation for chromogenic, fluorescent, or HRP-based detection workflows. Useful in studies of lipid mediator biosynthesis, keratinocyte and sebocyte differentiation programs, and tumor-microenvironment signaling contexts where 15-LOX-2 expression has been reported to be altered in prostate, breast, esophageal, and colorectal tissue.