Anti-ALKBH2 Antibody

Supplied as 50 µl of unconjugated rabbit polyclonal IgG, this Antibodies.com primary antibody targets the AlkB homolog 2 (ALKBH2) DNA repair enzyme. Validated for Western blot (WB) applications, it detects endogenous ALKBH2 in human and mouse samples, supporting research into direct reversal of alkylation damage, base excision repair pathways, and genome stability.

ALKBH2 is a Fe(II)/2-oxoglutarate-dependent dioxygenase that demethylates N1-methyladenine and N3-methylcytosine lesions in single-stranded and double-stranded DNA. Raised in a rabbit host, the polyclonal antibody recognizes multiple epitopes on this nuclear protein, while the unconjugated format allows flexible secondary labeling with anti-rabbit IgG reagents conjugated to HRP, biotin, or fluorophores.

Recommended uses include chromatin biology studies, DNA damage response investigations, and analyses of alkylation-induced mutagenesis. For handling, aliquot the reagent upon arrival, refrigerate at short-term antibody storage conditions, and avoid repeated freeze-thaw cycles to preserve titer. This product is intended for research use only.