Anti-Aldolase C Antibody

Raised in rabbit against the C-terminal glycolytic isozyme, this unconjugated polyclonal reagent from Antibodies.com supports both western blot and ELISA workflows on human, mouse, and rat samples.

Aldolase C is the brain-predominant aldolase isoform, enriched in cerebellar Purkinje cell bodies and hippocampal neurons, where it is widely used as a lineage and zonation marker in neuroanatomy studies. Beyond neuroscience, the antibody is applied to metabolic reprogramming research, since ALDOC participates in fructose-1,6-bisphosphate turnover and shifts in glycolytic flux are characteristic of several cancer cell types.

Each vial is supplied as 100 µl of liquid antiserum, unconjugated for flexible labelling, and is ready for downstream HRP- or fluorophore-based detection chemistries. Researchers studying cerebellar development, glial versus neuronal lineage, or cancer metabolism will find the reagent useful for tracking isoform-specific expression patterns where aldolase A and aldolase B cross-reactivity must be minimised.