Anti-ALDH3B2 Antibody

This rabbit polyclonal antibody specifically recognizes aldehyde dehydrogenase 3 family member B2 (ALDH3B2), an enzyme implicated in cellular aldehyde detoxification and oxidative stress responses. Produced by Antibodies.com, the reagent is supplied as an unconjugated 100 µl volume at 1 mg/ml in phosphate-buffered saline (PBS) containing 0.05% sodium azide, adjusted to approximately pH 7.2. It is validated for Western blot (WB) and immunohistochemistry (IHC) workflows, with confirmed reactivity against human, mouse, and rat tissue specimens, supporting cross-species comparative studies in translational research.

ALDH3B2 belongs to a conserved enzyme superfamily that catalyzes NAD(P)+-dependent oxidation of aldehyde substrates. Altered expression of this isozyme has been reported in epithelial tumors and in cellular models of xenobiotic stress. Researchers can use this primary antibody to probe endogenous ALDH3B2 levels in cell lysates by Western blot and in fixed tissue sections by immunohistochemistry, enabling investigations into metabolic detoxification pathways and tumor marker profiling. The polyclonal format offers multi-epitope recognition, supporting reproducible detection across these applications.

For storage, keep the vial refrigerated and protect from light; aliquot upon arrival if repeated freeze-thaw cycles are anticipated. Short-term handling at room temperature is acceptable during active bench work. Intended for research use only.