Anti-ALDH3B1 Antibody

The ALDH3B1 protein is a cytosolic aldehyde dehydrogenase that belongs to the ALDH3 subfamily and catalyzes the NAD(P)+-dependent oxidation of aldehydes generated during lipid peroxidation and xenobiotic metabolism. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human ALDH3B1 and is supplied as a 100 µl liquid aliquot, sufficient for multiple western blot and immunohistochemistry experiments.

The antibody is reactive with human ALDH3B1 and validated for WB and IHC workflows, supporting studies of aldehyde detoxification pathways, oxidative stress responses, and reports linking ALDH3B1 expression to drug-resistance phenotypes in prostate and breast cancer cell lines. The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which can be useful when probing tissue sections where expression varies between cell types or between normal and tumor regions.

Because it is supplied unconjugated, the antibody can be paired with HRP- or fluorophore-conjugated secondary reagents to match different detection chemistries, from chemiluminescent western blot imaging to chromogenic immunohistochemistry on formalin-fixed paraffin-embedded sections. Researchers comparing ALDH3 family members, characterizing ALDH3A1, ALDH3A2, and ALDH3B1 across tissues, or profiling aldehyde-metabolizing capacity in cell models will find this primary antibody a flexible addition to their workflow.