Anti-ALDH1A2 Antibody

A rabbit-derived primary antibody from Antibodies.com detects aldehyde dehydrogenase 1A2 (ALDH1A2), also called RALDH2. This enzyme catalyzes the final oxidative step in retinoic acid biosynthesis, converting retinaldehyde to retinoic acid. The antibody supports research into retinoid signaling, including retinoic acid gradient formation during embryonic development and the maintenance of adult tissues.

The unconjugated polyclonal IgG preparation binds multiple epitopes on the target protein. It is validated for Western blot and immunohistochemistry, enabling researchers to examine ALDH1A2 abundance in denatured protein extracts and localize expression in fixed tissue sections. Reactivity with human, mouse, and rat samples supports comparative studies across these species. Relevant applications include developmental biology, cancer research, investigations of tissue homeostasis, and studies of stem cell differentiation.

Each vial contains 50 µl of liquid antibody. The unconjugated format allows researchers to select a compatible labeled secondary reagent or create a customized detection scheme according to the experimental workflow. The polyclonal composition can provide broad recognition when mapping ALDH1A2 expression or comparing protein levels among samples.

For handling, aliquot the reagent upon arrival, store it at -20°C for longer-term use, and avoid repeated freeze-thaw cycles. Short-term working stocks may be refrigerated for routine experiments while maintaining antibody activity.