Anti-ALDH1A1 Antibody

Raised in rabbit, this unconjugated polyclonal antibody from Antibodies.com targets Aldehyde Dehydrogenase 1 Family Member A1 (ALDH1A1), a cytosolic NAD+-dependent enzyme of approximately 55 kDa that converts retinaldehyde to retinoic acid and supports retinoic acid signaling in many tissues.

Supplied as 100 µl of liquid, the antibody is validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) on Human, Mouse, and Rat samples. ALDH1A1 is broadly expressed in liver, kidney, lung, testis, and neural tissue and is widely used as a marker of cancer stem cell populations in breast, lung, colon, and pancreatic tumor models.

Researchers apply the reagent to study retinoid metabolism, xenobiotic detoxification, acetaldehyde clearance, stem cell biology, and the role of ALDH1A1 in chemoresistance and tumor initiation across epithelial, hepatic, and neural systems.